DISCO is a VUV to visible beamline dedicated to biochemistry, chemistry and cell biology. The spectral region is optimised between 60 and 700 nm with conservation of the natural polarization of the light.
Three endstations are operated around a common scientific topic : Biomolecular investigations, with special emphasis on proteins, particularly membrane proteins:
- A circular dichroism endstation in the VUV range which opens new fields in the investigation of biological molecules, with, in particular, the possibility to follow rapid kinetics such as proteins folding and unfolding in real time,.
- An endstation for mass spectrometry of non-soluble molecules based on VUV photoionization with new opportunities for proteomics and photochemistry of hydrophobic molcules.
- An imaging endstation for biological (living cells) and material applications with new possibilities of excitation and detection, also allowing biomedical investigation of normal and tumoral tissues moreover, new paradigms in autofluorescence diagnosis appear and "abandonned" molecules that fluoresce only in the UV can be used as probes.
Two endstations are always working in parallel, the imaging one and SRCD or APEX.